FIGURE

Fig. 1

ID

ZDB-FIG-150120-1

Publication

Smith et al., 2014 - Contact-Mediated Inhibition Between Oligodendrocyte Progenitor Cells and Motor Exit Point Glia Establishes the Spinal Cord Transition Zone

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

PNS glia restrict OPC membrane processes in the PNS.

(A) Schematic of zebrafish spinal motor roots showing the CNS (green) consisting of the spinal cord and brain and the PNS (red). Insets show zoomed representations of a single spinal motor nerve root with motor axons (red), OPCs (orange), and PNS glia (yellow). Lateral and cross-section views are shown. (B) Frames captured from a 14-h time-lapse video beginning at 58 hpf in a Tg(sox10:eos) embryo. Numbers in upper right corners denote time lapsed from the first frame of the figure. (A) At approximately 68 hpf (00:00), peripheral glial cells (arrow) and OPCs (asterisk) can be seen. Just 2 min later (00:02), an OPC process (arrowhead/orange box) extended out of the spinal cord, contacted the motor root glial cell (arrow), and quickly retracted, all within 6 min. Traced schematic below shows spinal cord (grey) and OPC (red), at the corresponding times. All images are lateral views of the motor and sensory root with dorsal to the top and anterior to the left. Scale bar, 15 µm.

Expression Data

Gene:	Eos
Fish:	w9Tg
Condition:	chemical treatment: N-phenylthiourea
Anatomical Terms:	glial cell oligodendrocyte
Stage:	Pec-fin

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Biol.