ZFIN ID: ZDB-FIG-141112-2
Ferrari et al., 2014 - FAS/FASL are dysregulated in chordoma and their loss-of-function impairs zebrafish notochord formation. Oncotarget   5(14):5712-5724 Full text @ Oncotarget
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: 64-cell to Adult
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Prim-5 to Day 5

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
fas AB standard conditions 64-cell whole organism RTPCR
16-cell whole organism RTPCR
30%-epiboly whole organism RTPCR
Shield whole organism RTPCR
1-4 somites to 26+ somites whole organism RTPCR
Prim-5 notochord RTPCR
Prim-5 whole organism RTPCR
Long-pec notochord RTPCR
Long-pec whole organism RTPCR
Protruding-mouth whole organism RTPCR
Day 5 whole organism RTPCR
Days 7-13 whole organism RTPCR
Days 14-20 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult brain RTPCR
Adult eye RTPCR
Adult gut RTPCR
Adult ovary RTPCR
faslg AB standard conditions 16-cell whole organism RTPCR
64-cell whole organism RTPCR
30%-epiboly Not Detected whole organism RTPCR
Shield Not Detected whole organism RTPCR
1-4 somites to 26+ somites Not Detected whole organism RTPCR
Prim-5 whole organism RTPCR
Long-pec notochord RTPCR
Long-pec whole organism RTPCR
Protruding-mouth whole organism RTPCR
Day 5 whole organism RTPCR
Days 7-13 whole organism RTPCR
Days 14-20 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult brain RTPCR
Adult eye RTPCR
Adult gut RTPCR
Adult ovary RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO1-fas standard conditions Prim-5 - Day 5 head edematous, abnormal
Prim-5 - Day 5 notochord bent, abnormal
Prim-5 - Day 5 pericardium edematous, abnormal
Prim-5 - Day 5 post-vent region increased curvature, abnormal
AB + MO1-fas + MO1-faslg standard conditions Prim-5 head edematous, abnormal
Prim-5 notochord bent, abnormal
Prim-5 pericardium edematous, abnormal
Prim-5 post-vent region increased curvature, abnormal
Long-pec head edematous, abnormal
Long-pec notochord bent, abnormal
Long-pec pericardium edematous, abnormal
Long-pec post-vent region increased curvature, abnormal
Protruding-mouth head edematous, abnormal
Protruding-mouth notochord bent, abnormal
Protruding-mouth pericardium edematous, abnormal
Protruding-mouth post-vent region increased curvature, abnormal
Day 5 head edematous, abnormal
Day 5 notochord bent, abnormal
Day 5 pericardium edematous, abnormal
Day 5 post-vent region increased curvature, abnormal
AB + MO1-faslg standard conditions Prim-5 - Day 5 head edematous, abnormal
Prim-5 - Day 5 notochord bent, abnormal
Prim-5 - Day 5 pericardium edematous, abnormal
Prim-5 - Day 5 post-vent region increased curvature, abnormal
Full text @ Oncotarget