Gene
faslg
- ID
- ZDB-GENE-070410-16
- Name
- Fas ligand (TNF superfamily, member 6)
- Symbol
- faslg Nomenclature History
- Previous Names
-
- FasL (1)
- zgc:162027
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have tumor necrosis factor receptor binding activity. Involved in notochord development. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in several diseases, including cholangiocarcinoma; chronic myeloid leukemia; diabetes mellitus (multiple); pancreatic cancer (multiple); and pre-eclampsia (multiple). Is expressed in brain; eye; gut; notochord; and ovary. Orthologous to human FASLG (Fas ligand).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Ferrari et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autoimmune lymphoproliferative syndrome | Alliance | Autoimmune lymphoproliferative syndrome, type IB | 601859 |
| lung cancer | Alliance | {Lung cancer, susceptibility to} | 211980 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Tumour necrosis factor domain | Tumour necrosis factor-like domain superfamily |
|---|---|---|---|
|
UniProtKB:Q0PKX7
|
268 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available