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ZFIN ID: ZDB-FIG-141106-1
Connors et al., 1999 - The role of tolloid/mini fin in dorsoventral pattern formation of the zebrafish embryo. Development (Cambridge, England)   126(14):3119-3130
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage Range: 1-4 somites to Adult

Fig. 3

Morphological defects visible in live mini fin mutant embryos. (A,B) 1-somite-stage mfn mutant (B) displays an oblong shape relative to wild type (A). 5- somite-stage wild-type (C) and mfn (D) mutant embryos. Arrows denote the tail bud length and the asterisk marks a protrusion of the tail bud seen in the mutant (D). 24 hpf wild type (E) and tails of mfn mutants exhibiting (F) a partial loss of tail fin (between the arrows) that extends to the dorsal side, (G) partial loss of the ventral fin with a bifurcation in the tail, (H) near complete absence of ventral fin and a kink in the tail. This occasionally observed kink is associated with a disruption in the notochord, which is also observed in the more strongly dorsalized mutant lost-a-fin (Solnica-Krezel et al., 1996, our unpublished observations). (I,J) mfn homozygous adult fish. Homozygous adult exhibiting a near wild-type appearance (I). Note that a pigmented stripe in the tail is disrupted in this mutant, a trait characteristic of mfn homozygous fish. Other adult mutants may display a partial or full (J) loss of their tail fin. All are lateral views. (A-D) dorsal to the right, (E-J) dorsal to the top. AF, anal fin; TF, tail fin; DF, dorsal fin.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
tll1tb241c/tb241c(TU) standard conditions Prim-5 post-vent region bifurcated, abnormal
Prim-5 ventral fin fold absent, abnormal
Prim-5 whole organism dorsal-ventral axis absent, abnormal
tll1tc263a/tc263a(TU) standard conditions Prim-5 post-vent region bifurcated, abnormal
Prim-5 ventral fin fold absent, abnormal
Prim-5 whole organism dorsal-ventral axis absent, abnormal
tll1tf215a/tf215a(TU) standard conditions Prim-5 post-vent region bifurcated, abnormal
Prim-5 ventral fin fold absent, abnormal
Prim-5 whole organism dorsal-ventral axis absent, abnormal
tll1tm124a/tm124a(TU) standard conditions 1-4 somites whole organism oblong, abnormal
5-9 somites tail bud decreased length, abnormal
Prim-5 post-vent region bifurcated, abnormal
Prim-5 ventral fin fold absent, abnormal
Prim-5 whole organism dorsal-ventral axis absent, abnormal
Adult caudal fin absent, abnormal
tll1tn217b/tn217b(TU) standard conditions Prim-5 post-vent region bifurcated, abnormal
Prim-5 ventral fin fold absent, abnormal
Prim-5 whole organism dorsal-ventral axis absent, abnormal
tll1tt203a/tt203a(TU) standard conditions Prim-5 post-vent region bifurcated, abnormal
Prim-5 ventral fin fold absent, abnormal
Prim-5 whole organism dorsal-ventral axis absent, abnormal
tll1tv9b/tv9b(TU) standard conditions Prim-5 post-vent region bifurcated, abnormal
Prim-5 ventral fin fold absent, abnormal
Prim-5 whole organism dorsal-ventral axis absent, abnormal
tll1ty130a/ty130a(TU) standard conditions Prim-5 post-vent region bifurcated, abnormal
Prim-5 ventral fin fold absent, abnormal
Prim-5 whole organism dorsal-ventral axis absent, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright.