ZFIN ID: ZDB-FIG-140807-18
Zhang et al., 2014 - Heme acts through the Bach1b/Nrf2a-MafK pathway to regulate exocrine peptidase precursor genes in porphyric zebrafish. Disease models & mechanisms   7(7):837-45 Full text @ Dis. Model. Mech.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Term:
Stage: Protruding-mouth

Fig. 2 Expression of bach1b, nrf2a and mafK in the exocrine pancreas as shown by using double in situ hybridization. The fluorescein-labeled probe indicated the expression areas (red) of try, an exocrine pancreas marker (A,B,C). Digoxigenin-labeled probes indicated the expression areas (blue) of bach1b (D,E,F), nrf2a (G,H,I) and mafK (J,K,L). The colocalization of try with bach1b (M,N,O), nrf2a (P,Q,R), or mafK (S,T,U) in the exocrine pancreas was shown by using double in situ hybridization. Longitudinal sections are shown in A,D,G,J,M,P,S; sagittal sections are shown in B,E,H,K,N,Q,T; and cross-sections are shown in C,F,I,L,O,R,U. All larvae examined were at 84 hpf. Arrows indicate the exocrine pancreas.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
bach1b WT standard conditions Protruding-mouth exocrine pancreas ISH
mafk WT standard conditions Protruding-mouth exocrine pancreas ISH
nfe2l2a WT standard conditions Protruding-mouth exocrine pancreas ISH
prss1 WT standard conditions Protruding-mouth exocrine pancreas ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
ZFIN wishes to thank the journal Disease models & mechanisms for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Dis. Model. Mech.