ZFIN ID: ZDB-FIG-140626-2
Wei et al., 2014 - Transcriptional factors Smad1 and Smad9 act redundantly to mediate zebrafish ventral specification downstream of Smad5. The Journal of biological chemistry   289(10):6604-18 Full text @ J. Biol. Chem.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: 1-cell to 75%-epiboly
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Prim-15

Fig. 1 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
smad1 WT standard conditions 1-cell Not Detected whole organism ISH
30%-epiboly Not Detected whole organism ISH
50%-epiboly whole organism ventral side ISH
75%-epiboly whole organism ventral side ISH
smad5 WT standard conditions 1-cell whole organism ISH
50%-epiboly whole organism ISH
30%-epiboly whole organism ISH
75%-epiboly whole organism ventral side ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-smad5 standard conditions Prim-15 dorsal/ventral pattern formation process quality, abnormal
Prim-15 whole organism wholly dorsalized, abnormal
WT + MO1-smad5 + MO3-smad1 standard conditions Prim-15 dorsal/ventral pattern formation process quality, abnormal
Prim-15 whole organism wholly dorsalized, abnormal
WT + MO3-smad1 standard conditions Prim-15 blood island has extra parts of type erythroid lineage cell, abnormal
Prim-15 blood island morphology, abnormal
Prim-15 central nervous system degenerate, abnormal
Prim-15 extension morphology, abnormal
Full text @ J. Biol. Chem.