FIGURE

Fig. 3

ID

ZDB-FIG-140507-7

Publication

Fero et al., 2014 - Impaired embryonic motility in dusp27 mutants reveals a developmental defect in myofibril structure

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Morpholino knockdown of dusp27 phenocopies y241 mutants. (A) Validation of morpholino efficacy for dusp27 knockdown using a dusp27 N-terminal sequence fused to GFP. (B) Morphology of embryos injected with control morpholino (top panel) or 1 ng of morpholino against dusp27 (bottom panel). Embryos show pronounced edema (asterisk). (C) Spontaneous coiling in embryos injected with control morpholino (black, n=11), 1 ng dusp27 morpholino (blue, n=9) or 2 ng dusp27 morpholino (gray, n=9). Inset, average coiling during 24–28 hpf for the same larvae. *P<0.01. Graphs show mean ± s.e.m.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	TL + MO1-dusp27
Knockdown Reagent:	MO1-dusp27
Observed In:	heart musculoskeletal movement
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.