FIGURE

Fig. 3

ID

ZDB-FIG-140421-21

Publication

Zhang et al., 2014 - Quantitative phenotyping-based in vivo chemical screening in a zebrafish model of leukemia stem cell xenotransplantation

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Fig. 3

LSC ability in zebrafish xenograft.

(A) Typical images of cancer xenografts at 6 days post-injection (dpi). Scale bar: 1.0 mm. The implanted tumor is framed in yellow (the magnification shows the outlined area). (B) In 6-dpi xenografts, ALDH+ cells exhibited greater tumorigenicity than ALDH- cells. P<0.05, based on 3 independent experiments. (C) The distal (tail region) migration of ALDH+ cells was greater than that of ALDH- cells. P<0.05, based on 3 independent experiments. (D) In single cell xenotransplants, ALDH+ cells proliferated at 7 dpi whereas ALDH- cells were no longer detectable. Scale bar: 1.0 mm. The implanted tumor is framed in yellow (the magnification shows the outlined area).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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