FIGURE

Fig. 3

ID

ZDB-FIG-140325-62

Publication

Maurya et al., 2013 - Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Kif7 acts downstream of Smo to control Hh target genes.

(A,B,C) Parasagittal optical sections of 30 hpf wild-type (A), smo mutant (B) and smo;MZkif7 (C) double mutant embryos stained with mAb4D9 (green) and Prox1 (red). Scale bar 50 μm. (D,E,F) Lateral view at the level of the yolk extension of 36 hpf wild-type (D), cyclopamine exposed (E) and MZkif7; cyclopamine (CycA) exposed (F) hybridized with a probe for c-myb RNA, marking hematopoietic stem cells in the ventral floor of the dorsal aorta. Scale bar 50 µm (detail in insets; scale bar 10 μm).

Expression Data

Genes:	myb prox1a
Antibody:	Ab1-eng
Fish:	WT kif7^i271/i271 smo^b641/b641 smo^b641/b641; kif7^i271/i271
Condition:	chemical treatment: Cyclopamine
Anatomical Terms:	fast muscle cell muscle pioneer myotome slow muscle cell ventral wall of dorsal aorta hematopoietic stem cell
Stage Range:	Prim-15 to Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT kif7^i271/i271 smo^b641/b641 smo^b641/b641; kif7^i271/i271
Condition:	chemical treatment: Cyclopamine
Observed In:	muscle pioneer myotome slow muscle cell ventral wall of dorsal aorta hematopoietic stem cell
Stage Range:	Prim-15 to Prim-25

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.