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Fig. 3
Kif7 acts downstream of Smo to control Hh target genes.
(A,B,C) Parasagittal optical sections of 30 hpf wild-type (A), smo mutant (B) and smo;MZkif7 (C) double mutant embryos stained with mAb4D9 (green) and Prox1 (red). Scale bar 50 μm. (D,E,F) Lateral view at the level of the yolk extension of 36 hpf wild-type (D), cyclopamine exposed (E) and MZkif7; cyclopamine (CycA) exposed (F) hybridized with a probe for c-myb RNA, marking hematopoietic stem cells in the ventral floor of the dorsal aorta. Scale bar 50 µm (detail in insets; scale bar 10 μm).
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