FIGURE

Fig. 3

ID

ZDB-FIG-140324-16

Publication

Wang et al., 2013 - Impact of a combined high cholesterol diet and high glucose environment on vasculature

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Lipid accumulation in vasculature.

A: Apparent lipid accumulation (yellow) was observed. (a), (b), (c), (d) panels respectively show lipid deposits in different experimental groups. (a) Control group; (b) HCD-HG group; (c) Pioglitazone treatment group; (d) Metformin treatment group. White arrows point out the locations of lipid deposits. Scale bar = 40 μm. B: Areas of the lipid accumulation were selected as the region of interest (ROI), and estimated by measuring the dimension of ROI. Using the Student t test, we found that the amount of lipid accumulation was significantly larger in the HCD-HG treated group than that in the control group (p<0.05). The addition of pioglitazone or metformin significantly reduced the lipid accumulation (p<0.05). Asterisk (*): Comparison of lipid accumulation between control group and HCD-HG group. Cross (†): Comparison of lipid accumulation between HCD-HG group and drug treatment groups, respectively.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One