Expression pattern of snail1 in spadetail embryos. (A-D) Posterior views; (E,F) lateral views. (A,B) 80% epiboly; (C,D) 10-somite stage; (E,F) 12-somite stage. (A,C,E) Wild-type embryos; (B,D,F) spadetail embryos. While snail1 RNA lines the lateral border of the embryonic shield in wild-type (A), it is missing in spadetail embryos (B). The axial mesoderm is broader in a spadetail embryo (C) than in a wild-type embryo (D). Wild-type embryos have extensive areas containing snail1 transcripts in the paraxial mesoderm and somites (E), while spadetail embryos have much less snail1 transcript in the paraxial region (F). In the mutant, snail1 transcript is present only in the tail bud and in a few cells scattered along the axial mesoderm.
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