FIGURE

Fig. 2

ID

ZDB-FIG-140226-13

Publication

Essers et al., 2014 - A comparative study of nucleostemin family members in zebrafish reveals specific roles in ribosome biogenesis

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Fig. 2

Morphology of ns family member mutants. Bright-field microscopy showing the morphological phenotypes of the mutants compared to a wild type sibling of gnl2 (there was no appreciable difference between wild type siblings of ns, gnl2, or gnl3l, therefore only gnl2 wild type siblings are shown for space reasons). The enlargement of the forebrain at 1 dpf is depicted with forked arrowheads. The inflation of the hindbrain ventricle is depicted at 5 dpf with arrowheads, and the cardiac edemas depicted with arrows. The size of the eyes at 5 dpf is illustrated with the white dotted circles.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gnl2^bw41c/bw41c gnl3^{hu3259/hu3259} gnl3l^{hi1437Tg/hi1437Tg}
Observed In:	eye forebrain ventricle fourth ventricle head integument pericardium posterior chamber swim bladder whole organism (all 8)
Stage Range:	Prim-5 to Day 5

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 385(2), Essers, P.B., Pereboom, T.C., Goos, Y.J., Paridaen, J.T., and Macinnes, A.W., A comparative study of nucleostemin family members in zebrafish reveals specific roles in ribosome biogenesis, 304-15, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.