Fig. 5
- ID
- ZDB-FIG-140107-32
- Publication
- Fernandes et al., 2013 - Orthopedia Transcription Factor otpa and otpb Paralogous Genes Function during Dopaminergic and Neuroendocrine Cell Specification in Larval Zebrafish
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Expression of crh in otpa and otpb single and double mutant larvae. Whole-mount in situ hybridization reveals loss of oxt, avp and trh expression in the preoptic region (arrowhead) of otpa;otpb double mutant larvae at 3 dpf. We detected oxt-expressing cells at ectopic locations within the diencephalon in otpa mutants (B2, asterisk). A reduction of trh-expressing cells in the preoptic region in otpa single mutants is detectable, (J2, arrowhead). Dorsal view, anterior at left. Scale bar is 50 μm. Abbreviations: H, hypothalamus; PO, preoptic region. |
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Stage: | Protruding-mouth |