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General Information
ZIRC
ZFIN ID: ZDB-FIG-131226-7
Yang et al., 2012 - alpha-Actinin2 is required for the lateral alignment of Z discs and ventricular chamber enlargement during zebrafish cardiogenesis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology   26(10):4230-4242 Full text @ FASEB J.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Long-pec

Fig. 7 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-tnnt2a standard conditions Long-pec cardiac muscle cell decreased size, normal
Long-pec cardiac muscle cell sarcomere disorganized, abnormal
Long-pec ventricular myocardium decreased volume, normal
WT + MO1-tnnt2a + MO5-actn2b standard conditions Long-pec cardiac muscle cell decreased amount, abnormal
Long-pec cardiac muscle cell decreased size, normal
Long-pec cardiac muscle cell sarcomere disorganized, abnormal
Long-pec cardiac muscle cell Z disc shape, abnormal
Long-pec heart contraction arrested, abnormal
Long-pec ventricular myocardium decreased volume, normal
WT + MO5-actn2b standard conditions Long-pec cardiac muscle cell decreased amount, abnormal
Long-pec cardiac muscle cell decreased size, abnormal
Long-pec cardiac muscle cell sarcomere disorganized, normal
Long-pec ventricular myocardium decreased volume, abnormal
Full text @ FASEB J.