FIGURE
Fig. 7
- ID
- ZDB-FIG-130826-64
- Publication
- Costa et al., 2013 - GRG5/AES Interacts with T-Cell Factor 4 (TCF4) and Downregulates Wnt Signaling in Human Cells and Zebrafish Embryos
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Fig. 7
GRG5/AES overexpression leads to ventralization of zebrafish embryos. (A–D) Lateral view, dorsal to the right, of 10hpf-stage embryos. (A) Control uninjected; (B) Injected with 250pg of grg5/aes mRNA; arrowhead: anterior end of the neural plate with formation of the “polster” in the prospective head region; (C–D) Injected with 100pg of an activated β-catenin mRNA. Black arrows: ectopic dorsal axis; E-F) Whole-mount in situ hybridization for chordin expression at 70% epiboly uninjected (E) and grg5/aes-injected (F) embryos. |
Expression Data
| Gene: | |
|---|---|
| Fish: | |
| Anatomical Term: | |
| Stage Range: | Shield to 75%-epiboly |
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Full text @ PLoS One