FIGURE
Fig. S3
- ID
- ZDB-FIG-130813-13
- Publication
- Reimer et al., 2013 - Dopamine from the Brain Promotes Spinal Motor Neuron Generation during Development and Adult Regeneration
- Other Figures
- All Figure Page
- Back to All Figure Page
Fig. S3
(related to Fig. 3) D4a receptor knock down reduces the number of different motor neuron classes. Lateral views at 33 hpf are shown. A: D4a knock down attenuates islet-1:GFP+ motor neuron development, which is not rescued by NPA (drug exposure 24 to 56 hpf; ANOVA, ***P < 0.0001). B: Numbers of HB9:GFP+ motor neurons are significantly reduced by morpholino treatment (24 to 33 hpf). C: Knock down of d4a had no effect on motor neuron numbers at segment 16-17, when TH1+ axons had only reached trunk segment 7. Error bars represent SEM. Scale bars: 50 μm. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Developmental Cell, 25(5), Reimer, M.M., Norris, A., Ohnmacht, J., Patani, R., Zhong, Z., Dias, T.B., Kuscha, V., Scott, A.L., Chen, Y.C., Rozov, S., Frazer, S.L., Wyatt, C., Higashijima, S., Patton, E.E., Panula, P., Chandran, S., Becker, T., and Becker, C.G., Dopamine from the Brain Promotes Spinal Motor Neuron Generation during Development and Adult Regeneration, 478-491, Copyright (2013) with permission from Elsevier. Full text @ Dev. Cell