FIGURE

Fig. S2

ID

ZDB-FIG-130719-19

Publication

Mahmood et al., 2013 - Generation and validation of a zebrafish model of EAST (Epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome

Other Figures

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Fig. S2

Kcnj10b is expressed in the brain and otic vesicles. Expression of kcnj10b, detected by in situ hybridization, is not evident at 24 hpf but becomes weakly ubiquitously expressed throughout the central nervous system by 30 hpf (A), which remains ubiquitous at 48 hpf (B), after which is becomes more highly expressed along ventricles and axon tracts throughout the midbrain and hindbrain, including the cerebellar plate (cp in F), whilst maintaining quite low levels of expression throughout the brain, including the retina (C-G). Expression is evident in the otic vesicle at 120 hpf (H), but is not evident in the pronephros, spinal cord, or lateral line. All images are whole mount with anterior to the left. All images show a lateral view except F, which is a dorsal view. Scale bar=100 μm.

Expression Data

Gene:	kcnj10b
Fish:	TL
Anatomical Terms:	central nervous system hindbrain midbrain otic vesicle retina ventricular system
Stage Range:	Prim-15 to Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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