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ZFIN ID: ZDB-FIG-130430-2
Choudhry et al., 2013 - DiGeorge Syndrome Gene tbx1 Functions through wnt11r to Regulate Heart Looping and Differentiation. PLoS One   8(3):e58145 Full text @ PLoS One
Observed In:
Stage Range: Prim-15 to Long-pec

Fig. S2 Proliferation defects in tbx1-/- mutants. (A, B) Confocal projections of hearts from cmlc2:gfp (all heart cells are green) embryos at 33 hpf stained with phospho-histone 3 antibody (proliferating cells are red). The insets in A and B show a magnified view of a co-labeled cell (yellow). (C, D) Plots showing the total (C) and proliferating (D) number of cells in WT and tbx1-/- mutants. N is the total number of embryos. Arrows point to the AVC; v, ventricle; a, atrium. Scale bar: 25 μm.

Gene Expression DetailsNo data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
tbx1tm208/tm208; twu34Tg standard conditions Prim-15 cell population proliferation decreased rate, abnormal
Long-pec cardiac muscle cell decreased amount, abnormal
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One