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ZIRC
ZFIN ID: ZDB-FIG-130430-2
Choudhry et al., 2013 - DiGeorge Syndrome Gene tbx1 Functions through wnt11r to Regulate Heart Looping and Differentiation. PLoS One   8(3):e58145 Full text @ PLoS One
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage Range: Prim-15 to Long-pec

Fig. S2 Proliferation defects in tbx1-/- mutants. (A, B) Confocal projections of hearts from cmlc2:gfp (all heart cells are green) embryos at 33 hpf stained with phospho-histone 3 antibody (proliferating cells are red). The insets in A and B show a magnified view of a co-labeled cell (yellow). (C, D) Plots showing the total (C) and proliferating (D) number of cells in WT and tbx1-/- mutants. N is the total number of embryos. Arrows point to the AVC; v, ventricle; a, atrium. Scale bar: 25 μm.

Gene Expression DetailsNo data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
tbx1tm208/tm208; twu34Tg standard conditions Prim-15 cell population proliferation decreased rate, abnormal
Long-pec cardiac muscle cell decreased amount, abnormal
Acknowledgments:
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One