FIGURE

Fig. 4

ID

ZDB-FIG-130220-14

Publication

Luo et al., 2012 - Midkine-A functions upstream of Id2a to regulate cell cycle kinetics in the developing vertebrate retina

Other Figures

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Fig. 4

Conditional over-expression of Mdka. (A) Induced fluorescence in a Tg(pHSP70/4:mdka:egfp) larva at 72 hpf after heat shock treatment at 24 hpf. (B) Western blot stained with antibodies against EGFP showing induction of the fusion protein at 72 hpf after heat shock at 24 hpf. Tg, heat shock-treated, transgenic siblings; WT, heat shock-treated, wild-type embryos. (C) Mdka gain of function results in marked retinal overgrowth at 30 hpf, which is largely resolved by 72 hpf (D). Tg, heat shock-treated embryos from the Tg(pHSP70/4:mdka:egfp) line; WT, heat shock-treated wild-type siblings. Scale bar equals 50 μm.

Expression Data

Gene:	EGFP
Fish:	umk1Tg (AB) umk2Tg (AB) umk3Tg (AB)
Condition:	heat shock
Anatomical Term:	whole organism
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	umk1Tg (AB) umk2Tg (AB) umk3Tg (AB)
Condition:	heat shock
Observed In:	retina
Stage Range:	Prim-15 to Protruding-mouth

Phenotype Detail

Acknowledgments

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