FIGURE

Fig. 7

ID

ZDB-FIG-130208-23

Publication

Monk et al., 2013 - Mutation of sec63 in zebrafish causes defects in myelinated axons and liver pathology

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Fig. 7

sec63^st67 mutants develop liver steatosis. (A?F2) Lateral views of larvae stained with Oil Red O of the indicated genotypes and at the indicated developmental stages. (A?C) Arrows indicate the location of the liver in 5 dpf larvae. sec63^st67 mutant livers (C, n=7) are indistinguishable from wild-type (A, n=6) or heterozygous (B, n=12) livers. (D?F) Boxed regions denote the areas enlarged in D′?F′. (D′?F′) Outlines denote the liver in 8 dpf larvae. sec63^st67 mutant livers (F,F′, n=8) show stronger Oil Red O stain than wild-type (D,D′, n=14) or heterozygous (E,E′, n=34) livers. Scale bars: 200 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sec63^st67/st67
Observed In:	liver
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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