FIGURE

Fig. S5

ID

ZDB-FIG-121011-31

Publication

Kizil et al., 2012 - The chemokine receptor cxcr5 regulates the regenerative neurogenesis response in the adult zebrafish brain

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Fig. S5

cxcr5 translation-blocking antisense morpholino is functional. (A) Uninjected 2 day post-fertilization (dpf) embryos. (B) Control morpholino-injected embryos show no morphological phenotypes at 2 dpf. (C)cxcr5 antisense morpholinoinjected embryos display severe anomalies in axial extension and head development. (D)cxcr5 mRNA rescues the knockdown phenotypes when co-injected with antisense morpholinos. (E) Quantitative real-time PCR analysis of genes regulated by cxcr5, upon control and antisense morpholino injections. All the genes tested are upregulated after knocking down cxcr5. Percentages in A-D represent the ratio of embryos with gross morphological defects to the whole clutch size.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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