FIGURE

Fig. 2

ID

ZDB-FIG-120725-18

Publication

Lu et al., 2012 - Marine Cyclotripeptide X-13 Promotes Angiogenesis in Zebrafish and Human Endothelial Cells via PI3K/Akt/eNOS Signaling Pathways

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Fig. 2

The effects of X-13 on Human Umbilical Vein Endothelial Cell (HUVEC) invasion, migration and tube formation. HUVEC cultures were incubated with X-13 in the presence or absence of inhibitors for different periods in different assays and VEGF-treated cell cultures served as a positive control. Representative images show that X-13 induced HUVEC migration (A), invasion (B) and tube formation (C) in HUVEC cultures. L-NAME and LY294002 significantly inhibited X-13-induced cell invasion (A), migration (B) and tube formation (C). The bar chart shows quantitative data. Data are expressed as the mean ± SD. Results were obtained from four independent experiments (* X-13 vs. vehicle control group, p < 0.05; # LY294002 plus X-13 vs. X-13, p < 0.05; ☆ L-NAME plus X-13 vs. X-13, p < 0.05).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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