ZFIN ID: ZDB-FIG-120315-31
Clendenon et al., 2012 - Zebrafish cadherin-11 participates in retinal differentiation and retinotectal axon projection during visual system development. Developmental dynamics : an official publication of the American Association of Anatomists   241(3):442-454 Full text @ Dev. Dyn.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage Range: 20-25 somites to Prim-15

Fig. 3

Expression of early retinal specification markers in cdh11 morphant embryos. Zebrafish embryos were injected with either standard control morpholino oligonucleotide (MO, Control) or cdh11 MO. Whole-mount in situ hybridization labeling of embryos at different stages was performed using probes for markers retinal specification. Probes are shown in the bottom right corner of each panel. A,B:rx1 labeling of 21 hours postfertilization (hpf) control and cdh11 morphant embryos. Anterior views from a ventral perspective; a, anterior embryo border; d, dorsal surface. rx1 labeling was detected in control (A) and cdh11 morphant embryos (B). C,D:rx1 labeling was strongly detected in 30 hpf control and cdh11 morphant embryos. Dorsal view of 30 hpf embryos: anterior is top. E,F: Expression of shh, a marker of retinal stalk (arrows) differentiation, was strongly detected in 28 hpf control and cdh11 morphant embryos; lateral views, anterior is up.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-cdh11 standard conditions 20-25 somites eye decreased size, abnormal
Prim-5 optic stalk decreased size, abnormal
Prim-5 optic stalk shape, abnormal
Prim-15 eye decreased size, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Developmental dynamics : an official publication of the American Association of Anatomists for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Dev. Dyn.