FIGURE

Fig. 4

ID

ZDB-FIG-120126-37

Publication

Schepis et al., 2012 - αE-catenin regulates cell-cell adhesion and membrane blebbing during zebrafish epiboly

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Fig. 4

αE-catenin and E-cadherin depletion causes defects in radial intercalation (RI). (A-C) Confocal images from time-lapse movies at the most external epiblast layer of the animal pole at 50% epiboly. Membranes are labeled with mbGFP. Positive numbers indicate cells appearing in the focal plane (undergoing RI). Negative numbers indicate cells migrating back into the in lower epiblast layer (undergoing revRI). Scale bars: 8 μm. (D) Quantification of RI rate and revRI. n=9 embryos. ^#P<0.0005. Asterisk indicates not significant. Error bars indicate s.e.m.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-ctnna1 WT + MO3-cdh1
Knockdown Reagents:	MO1-ctnna1 MO3-cdh1
Observed In:	cell migration involved in gastrulation
Stage:	50%-epiboly

Phenotype Detail

Acknowledgments

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