Fig. S9
- ID
- ZDB-FIG-111201-12
- Publication
- Mich et al., 2011 - Hedgehog and retinoic acid signaling cooperate to promote motoneurogenesis in zebrafish
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RA promotes formation of RB sensory neurons independently of Hh signaling or Gli1 activity. (A-H) Wild-type (A-D) or MZsmo (E-H) embryos were uninjected (A,C,E,G) or injected with gli1 MO (B,D,F,H), treated with DMSO (A,B,E,F) or 100 nM RA (C,D,G,H), and then grown to 18 hpf. The embryos were then fixed and stained for isl2a transcripts to mark ventrally localized PMNs and dorsally localized RB sensory neurons. Arrowheads show RB neurons in the dorsal neural tube that are induced by RA in all conditions. Embryos are viewed laterally, anterior to the left. Scale bar: 200 μm. |