FIGURE

Fig. 2

ID

ZDB-FIG-111018-34

Publication

Lewis et al., 2011 - Celsr3 Is Required for Normal Development of GABA Circuits in the Inner Retina

Other Figures

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Fig. 2

Electroretinograms show an increase in the b-wave response in mutants at 6 dpf.

A) At 5 dpf, WT and zvm7^w65 responses are similar. B) At 6 dpf, zvm7^w65 eyes develop an increase in the b-wave. The b-wave was 176±13 µV in the WT (n = 30) and 260±48 µV in the zvm7^w65 fish at 6 dpf (n = 32) (p<.001). A) and B) show an average representative trace including at least 9 animals. C) WT and zvm7^w65 eyes have a similar light threshold response. Eyes were exposed to a millisecond light flash (arrow) at intensities differing by 0.5 log units (brightest = .41 mW). Amplitudes of mutant b-waves were larger at all light levels. Images show traces from a single representative animal.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	celsr3^w65/w65 (AB)
Observed In:	cellular response to light stimulus OFF-bipolar cell ON-bipolar cell
Stage Range:	Day 5 to Day 6

Phenotype Detail

Acknowledgments

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