FIGURE

Fig. 6

ID

ZDB-FIG-111018-29

Publication

Zhu et al., 2011 - Evaluation and application of modularly assembled zinc-finger nucleases in zebrafish

Other Figures

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Fig. 6

gata2a^um27 mutant embryos display defects in aorta morphogenesis. Confocal microangiography using Quantum Dots in Tg(kdrl:egfp)^la116 transgenic zebrafish embryos. Endothelial cells are green and vessel perfusion is red. (A,B) Cranial blood vessels in gata2a^um27 mutant (A) and wild-type (B) embryos. Lateral views, anterior to the left, dorsal is up. (C,D) Lateral dorsal aortae (arrows) in gata2a^um27 mutant (C) and wild-type (D) embryos. Dorsal views, anterior is up. (E,F) Trunk blood vessels in gata2a^um27 mutant (E) and wild-type (F) embryos. Lateral views, anterior to the left, dorsal is up. Segmental vessels are indicated by arrowheads and the dorsal aorta by an arrow; the asterisk indicates a region of aorta that failed to form.

Expression Data

Gene:	GFP
Fish:	la116Tg gata2a^um27/um27; la116Tg
Anatomical Term:	endothelial cell
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gata2a^um27/um27; la116Tg
Observed In:	blood vessel lumenization cranial vasculature dorsal aorta dorsal aorta morphogenesis lateral dorsal aorta trunk vasculature
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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