FIGURE

Fig. S11

ID

ZDB-FIG-110909-45

Publication

Johnson et al., 2011 - Vgll2a is required for neural crest cell survival during zebrafish craniofacial development

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Fig. S11

Apoptotic NCCs appear in the arches of vgll2a morphants but not in uninjected embryos at 24 hpf. Single-plane, confocal images showing the pharyngeal arches of a representative uninjected sox10:egfp embryo (A) and a sox10:egfp embryo injected with 5 ng vgll2a MO and 2 ng p53 MO (B) and stained with an anti-active caspase 3 antibody in lateral views. Apoptotic, anti-active caspase 3-postitive NCCs (arrow), were only observed in the arches of vgll2a morphants at 24 hpf. Arches are numbered 1?4. Anterior is to the left in both panels.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 357(1), Johnson, C.W., Hernandez-Lagunas, L., Feng, W., Melvin, V.S., Williams, T., and Artinger, K.B., Vgll2a is required for neural crest cell survival during zebrafish craniofacial development, 269-81, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.