FIGURE

Fig. S6

ID

ZDB-FIG-110516-73

Publication

Koshimizu et al., 2011 - Embryonic senescence and laminopathies in a progeroid zebrafish model

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Fig. S6

PPARγ mRNA expression in lamin A/C morphants. The expression of zebrafish PPARγ in the morphants was semi-quantitatively analyzed by single-embryo RT-PCR at 72 hpf. Two independent samples (lanes 1 and 2) for MO1 (both 5-mis and MO) and MO2 (both 5-mis and MO) were loaded in the lanes (upper picture panels). In quantitation (lower graph panel), the expression levels of PPARγ mRNA were significantly decreased in zLMNA-MO-injected (MO) embryos in comparison with the controls (5-mis) (P<0.01 for 5-mis versus MO in MO1 and MO2).

Expression Data

Gene:	pparg
Fish:	WT WT + MO3-lmna WT + MO5-lmna
Knockdown Reagents:	MO3-lmna MO5-lmna
Anatomical Term:	whole organism
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO3-lmna WT + MO5-lmna
Knockdown Reagents:	MO3-lmna MO5-lmna
Observed In:	fat cell fat cell differentiation
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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