FIGURE

Fig. 5

ID

ZDB-FIG-110221-32

Publication

Harrison et al., 2011 - The epigenetic regulator Histone Deacetylase 1 promotes transcription of a core neurogenic programme in zebrafish embryos

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Fig. 5

Expression of the Hdac1 neurogenic programme is stably attenuated in Hdac1ATG1 morphant embryos. (A) 6-somite stage (12 hpf) embryos and (B) 27 hpf embryos injected with standard Control + p53 morpholinos or Hdac1ATG1 + p53 morpholinos, analysed for expression of neurod4, ascl1b, neurod, dlb, lhx9 and sox2. Expression of neurod4, ascl1b, neurod, dlb and lhx9 was reduced in Hdac1-deficient embryos. In contrast, the expression pattern of sox2, which did not exhibit a statistically significant change in transcript abundance in the microarray analysis, was unaltered in 12 hpf Hdac1ATG1 morphant embryos.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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