FIGURE

Fig. 1

ID

ZDB-FIG-110221-30

Publication

Harrison et al., 2011 - The epigenetic regulator Histone Deacetylase 1 promotes transcription of a core neurogenic programme in zebrafish embryos

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Fig. 1

Hdac1 inhibits Histone acetylation and promotes H3K9 methylation levels in the zebrafish embryo. Levels of Hdac1 protein and covalently modified histones in hdac1 mutant (m) and wild-type (s) embryos aged 27, 33, 39, 48, 56, 73, 80 and 96 hpf, visualised by Western blot analysis using anti-Hdac1 and histone modification-specific antibodies. Hdac1 protein visualised with an anti-Hdac1 antibody is shown on the top row. Antibodies specific for the following histone modifications were: Pan-acetyl lysine; acetyl-H3K9; dimethyl-H3K9, trimethyl-H3K4. An anti-H3 antibody was used as a loading control (bottom row).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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