FIGURE
Fig. S6
- ID
- ZDB-FIG-101117-44
- Publication
- Jiang et al., 2009 - Kinase activity-independent regulation of cyclin pathway by GRK2 is essential for zebrafish early development
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Fig. S6
Knockdown of GRK2 in zebrafish results in the cardiac malformation. Embryos were injected with 2-ng con-MO, GRK2-MO, or coinjected with 0.15-ng bovine GRK2 or K220R mRNA. Photos were taken at 48 hpf and 200 embryos were counted for each group as a pool. GRK2-MO-treated embryos displayed stretched heart tube, incomplete heart loops, and pericardial edema. Hearts of GRK2 morphants beat weakly, and the blood in circulation was deficient. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage: | Long-pec |
Phenotype Detail
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Full text @ Proc. Natl. Acad. Sci. USA