FIGURE

Fig. 2

ID

ZDB-FIG-101111-34

Publication

Therapontos et al., 2010 - Zebrafish notch signalling pathway mutants exhibit trunk vessel patterning anomalies that are secondary to somite misregulation

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Fig. 2

ISV defects in aei, bea, and des Notch mutant embryos at 24, 48, 72, and 96 hpf. A–P: Fluorescence images of the middle portion of the zebrafish embryo as indicated in Q. TG(fli1:egfp)y1 (A,E,I,M); aei (B,F,J,N), bea (C,G,K,O), and des (D,H,L,P) embryos at 24 (A-D), 48 (E–H), 72 (I-L), and 96 (M-P) hpf. The vascular patterning defects do not recover over time. The regularity of ISV sprouting in control embryos is highlighted by white arrowheads (A,E,I,M). Mutant ISVs show irregular spacing (white arrowheads), abnormal paths (white arrows), and aberrant branching patterns (white asterisks). The positions of the DA, PCV, ISVs, and DLAV are indicated. Scale bar = 100 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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