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ZIRC
ZFIN ID: ZDB-FIG-100917-2
Grandel et al., 2000 - dackel acts in the ectoderm of the zebrafish pectoral fin bud to maintain AER signaling. Development (Cambridge, England)   127(19):4169-4178
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage Range: Prim-5 to Day 4

Fig. 1 Phenotype of dak and syu mutants at 72 h (A,B), 38 h (C,D) and 96 h (E-H): (A,C,E) Wild-type (wt), (B,D,F) dak-, (G) syutq252, (H) syut4. (A,B) anterior is towards the left, (C,D) anterior is towards the left, view from distal. Note that the wt apical fold in C produces a ‘line’ (arrow) where dorsal and ventral epidermis become juxtaposed. This ‘line’ is absent in the dak- bud in D. (E-H) distal is towards the right. Living dak- larvae lack functional pectoral fins at 72 h and fail to develop an apical fold at 38 h. At 96 h dak- larvae have developed a pectoral girdle that distinguishes them from syu hypomorphic and null mutants. cl, cleithrum; ed, endoskeletal disc; ff, fin fold; pg, shoulder girdle; pp, postcoracoid process.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
ext2to273b/to273b standard conditions Prim-5 - Prim-15 pectoral fin bud hypoplastic, abnormal
Prim-25 apical ectodermal ridge pectoral fin bud aplastic, abnormal
Protruding-mouth pectoral fin aplastic, abnormal
Day 4 fin fold pectoral fin bud absent, abnormal
Day 4 pectoral fin endoskeletal disc absent, abnormal
Day 4 pectoral girdle decreased size, abnormal
ext2tw25e/tw25e standard conditions Prim-5 - Prim-15 pectoral fin bud hypoplastic, abnormal
Prim-25 apical ectodermal ridge pectoral fin bud aplastic, abnormal
Protruding-mouth pectoral fin aplastic, abnormal
Day 4 fin fold pectoral fin bud absent, abnormal
Day 4 pectoral fin endoskeletal disc absent, abnormal
Day 4 pectoral girdle decreased size, abnormal
shhaDf(Chr07)t4/t4 standard conditions Day 4 cleithrum decreased size, abnormal
Day 4 pectoral fin endoskeletal disc absent, abnormal
Day 4 pectoral girdle absent, abnormal
shhatq252/tq252 standard conditions Day 4 fin fold pectoral fin bud disorganized, abnormal
Day 4 pectoral fin endoskeletal disc decreased size, abnormal
Day 4 pectoral girdle morphology, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright.