FIGURE
Fig. 5
Fig. 5
pard3 depletion causes misorientation and delayed cilia growth. Sections of control (A–A″) and pard3 MO-injected (B–B2′) embryos at 12–13 som, immunolabeled with anti-Glu-tub, anti-γ-tub and anti-Ace-tub. Nuclei are labeled with DAPI. (A′, A″, B1–B2′) Higher magnifications of boxed areas in (A) and (B) respectively. Dashed lines: midline; arrows: orientation of cilia; arrowhead: centrosome not associated with an axoneme. Scale bar: 10 μm. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage: | 10-13 somites |
Phenotype Detail
Acknowledgments
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Reprinted from Developmental Biology, 341(2), Hong, E., Jayachandran, P., and Brewster, R., The polarity protein Pard3 is required for centrosome positioning during neurulation, 335-345, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.