FIGURE

Fig. 4

ID

ZDB-FIG-100309-78

Publication

Lorent et al., 2010 - Reiterative use of the notch signal during zebrafish intrahepatic biliary development

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Fig. 4

Liver cells respond to the Notch signal throughout larval development. A-F: Biliary expansion resumes upon reinitiation of Notch signaling associated with DAPT withdrawal. There is progressive increase in the complexity of the biliary network in 125-hpf larvae treated with DAPT for shorter intervals beginning at 53 hpf. All images are derived from larvae immunostained with the anti keratin-18 antibody. The gallbladder (g) is out of the plane of focus in D and E. p, pancreas.

Expression Data

Antibody:	Ab1-krt18
Fish:	TL
Condition:	chemical treatment: DAPT
Anatomical Terms:	extrahepatic duct gall bladder intrahepatic bile duct pancreas
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	TL
Condition:	chemical treatment: DAPT
Observed In:	intrahepatic bile duct development
Stage:	Day 5

Phenotype Detail

Acknowledgments

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