FIGURE

Fig. 1

ID

ZDB-FIG-091026-2

Publication

Hong et al., 2009 - FGF-dependent left-right asymmetry patterning in zebrafish is mediated by Ier2 and Fibp1

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

Ier2 and Fibp1 are Downstream of FGF. (A–F) Whole-mount in situ hybridization with ier2 (A–C) at 80% epiboly, and with fibp1 (D–F) at 60% epiboly stages after injection of control gfp RNA, 100 pg (A and D); fgf8 RNA, 5 pg (B and E); and dnfgfr4 RNA, 300 pg (C and F). (G and H) Physical interaction between Ier2 and Fibp1. Immunoprecipitation (IP) and immunoblotting (IB) are indicated. (I–L) Intracellular localization of Ier2 and Fibp1. Ier2 (I) and Fibp1 (J) are colocalized in the nucleus (K) after injection of epitope-tagged constructs into zebrafish embryos. (L) Merged image I–K

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA