FIGURE

Fig. S4

ID

ZDB-FIG-090710-41

Publication

Kategaya et al., 2009 - Bili inhibits Wnt/beta-catenin signaling by regulating the recruitment of axin to LRP6

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Fig. S4

The zebrafish homolog of Bili (zfBili) is expressed during embryogenesis. In situ hybridization using a sense (left column) and antisense probes (right column) were used to detect mRNA. (A) zfBili is expressed maternally as it is detected in the animal pole 4 h post-fertilization. (B) zfBili continues to be expressed ubiquitously at 50% epiboly. (C) 24 hpf zfBili remains ubiquitous but shows specific staining in the otic vesicle (arrow head). (D) Weak Bili expression in the tail at 36 hpf. (E) A second morpholino targeting zfBili (bilimo2) but not a control morpholino (como) enhances the Wnt8 overexpression phenotype (n = 50 for each condition). Embryos were scored as wt (green), small eyes (yellow), no eyes (orange) or severe (red). Data shown is representative from four independent experiments.

Expression Data

Gene:	frmd8
Fish:	WT
Anatomical Terms:	otic vesicle post-vent region whole organism
Stage Range:	Sphere to Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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