Gene
frmd8
- ID
- ZDB-GENE-090812-5
- Name
- FERM domain containing 8
- Symbol
- frmd8 Nomenclature History
- Previous Names
-
- zfBili (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Involved in anterior/posterior pattern specification; negative regulation of Wnt signaling pathway; and regulation of canonical Wnt signaling pathway. Predicted to localize to cytoskeleton; cytosol; and plasma membrane. Is expressed in otic vesicle and post-vent region. Orthologous to several human genes including FRMD8 (FERM domain containing 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Kategaya et al., 2009
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000299 | FERM domain |
| Domain | IPR019748 | FERM central domain |
| Domain | IPR019749 | Band 4.1 domain |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR014352 | FERM/acyl-CoA-binding protein superfamily |
| Homologous_superfamily | IPR035963 | FERM superfamily, second domain |
Domain Details Per Protein
| Protein | Length | Band 4.1 domain | FERM/acyl-CoA-binding protein superfamily | FERM central domain | FERM domain | FERM superfamily, second domain | PH-like domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F221
|
471 |
Interactions and Pathways
No data available
Plasmids
No data available