FIGURE

Fig. 5

ID

ZDB-FIG-090513-21

Publication

Trapani et al., 2009 - Synaptojanin1 is required for temporal fidelity of synaptic transmission in hair cells

Other Figures

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Fig. 5

Impaired vesicle recycling at ribbon synapses in mutant synj1 hair cells.

A) TEM micrographs of neuromast ribbon synapses (upper panel: wild-type ribbon; lower panel: synj1^Q296X mutant ribbon). B) Same micrographs as in (A) with white circles denoting tethered vesicles. Blue and orange circles highlight the reserve vesicles in the wild type and mutant synapses, respectively. Note the reduction of reserve pool vesicles in the mutant synapse. Arrow heads indicate examples of large coated vesicles. Scale bar, 200 nm. Number of large coated vesicles (C), tethered vesicles per 100 nm of ribbon perimeter (D), and reserve pool vesicles (E) within 450 nm of ribbon centers in neuromast hair cells (black bars: wild type; grey bars: synj1^Q296X).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	synj1^{tQ296X/tQ296X}
Observed In:	neuromast hair cell synaptic vesicle
Stage Range:	Protruding-mouth to Days 21-29

Phenotype Detail

Acknowledgments

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