FIGURE

Fig. 4

ID

ZDB-FIG-090127-42

Publication

Kizil et al., 2009 - Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration

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Fig. 4

smp is necessary for regenerative outgrowth. (A) Lobes transfected with smp antisense morpholino showed strong fluorescein labeling. (B) Transfection of mismatch morpholino. Solid black lines show extent of regeneration before transfection and dashed lines show level of amputations. Scale bar equals 200 μm. (C) The graph represents the proportional relationship between transfected and untransfected lobes from each fin. n = number of fins transfected and analyzed. ***: p-value < 0.001, Student's t-test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-fam53b WT + MO2-fam53b
Condition:	amputation: caudal fin
Knockdown Reagents:	MO1-fam53b MO2-fam53b
Observed In:	fin regeneration regenerating fin regenerating tissue
Stage:	Adult

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 325(2), Kizil, C., Otto, G.W., Geisler, R., Nüsslein-Volhard, C., and Antos, C.L., Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration, 329-340, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.