Morpholino
MO2-fam53b
- ID
- ZDB-MRPHLNO-090925-3
- Name
- MO2-fam53b
- Previous Names
-
- smp-Exon3-Intron3 splice morpholino (1)
- Target
- Sequence
-
5' - GAATATCTGCACTTACCCATGATTC - 3'
- Disclaimer
- Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
- Note
-
splice-blocker targeted to exon 3 - intron 3 junction
- Genome Resources
- None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO2-fam53b
No data available
Phenotype
Phenotype resulting from MO2-fam53b
Phenotype | Fish | Figures |
---|---|---|
trunk posterior region decreased length, abnormal | WT + MO2-fam53b + MO4-tp53 |
Fig. 1 ![]() |
Phenotype of all Fish created by or utilizing MO2-fam53b
Citations
- Bhattacharya, S., Gargiulo, D., Iovine, M.K. (2018) Simplet-dependent regulation of β-catenin signaling influences skeletal patterning downstream of Cx43. Development (Cambridge, England). 145(23):
- Kizil, C., Küchler, B., Yan, J.J., Özhan, G., Moro, E., Argenton, F., Brand, M., Weidinger, G., Antos, C.L. (2014) Simplet/Fam53b is required for Wnt signal transduction by regulating β-catenin nuclear localization. Development (Cambridge, England). 141:3529-39
- Kizil, C., Otto, G.W., Geisler, R., Nüsslein-Volhard, C., and Antos, C.L. (2009) Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration. Developmental Biology. 325(2):329-340
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