FIGURE

Fig. 1

ID

ZDB-FIG-090127-39

Publication

Kizil et al., 2009 - Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration

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Fig. 1

Expression of smp in the regenerating adult caudal fin. smp expression at different time points of caudal fin regeneration are shown from whole mounts (A–F) and coronal cryosections (G–J). (A) The gene is not expressed in unamputated (B) nor in regenerating fins 1 day post amputation (dpa). (C) By 2 dpa, smp is transcribed in the regenerating tissue distal to the amputation plane. Expression localizes to the distal portion of the regenerate by 3 dpa (D) as well as 4 dpa (E). (F) Transcript is down-regulated by 5 dpa. (G) In situ hybridization on cryosections of 2 dpa regenerating fin: smp expression in the mesenchyme (m) underlying the epithelial cap (ec) and basal epithelium (be) of the epidermis. (H) By 3 dpa, smp expression is located several tissues in the distal portion of the regenerate. (I) Higher magnification of distal fin regenerate. (J) Hybridization on 3 dpa fin with sense probe. The dashed line shows the amputation plane. Scale bars equal 100 μm.

Expression Data

Gene:	fam53b
Fish:	WT
Condition:	amputation: caudal fin
Anatomical Terms:	caudal fin regenerating tissue regenerating fin
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 325(2), Kizil, C., Otto, G.W., Geisler, R., Nüsslein-Volhard, C., and Antos, C.L., Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration, 329-340, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.