FIGURE

Fig. S1

ID

ZDB-FIG-090113-3

Publication

Jurynec et al., 2008 - Selenoprotein N is required for ryanodine receptor calcium release channel activity in human and zebrafish muscle

Other Figures

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Fig. S1

SepN genomic structure and morpholino inhibition of SepN expression. (a) Genomic structure of the zebrafish sepN locus containing conserved elements including a selenocysteine codon (Sec), a Sec Redefinition Element (SRE), and a selenocysteine insertion sequence (SECIS) element. * indicates stop codon; red bars indicate sbMOs; arrows indicate primers used to detect sepN transcripts by RT-PCR. (b) RT-PCR analysis of sepN transcripts in 24 hpf WT, MO1- or MO2-injected embryos. *,WT sepN amplicon; arrows, intron-included amplicons; m, markers. (c and d) sepN RNA levels are reduced in MO1-injected embryos. Lateral views with rostral left.

Expression Data

Gene:	selenon
Fish:	WT WT + MO5-selenon WT + MO6-selenon
Knockdown Reagents:	MO5-selenon MO6-selenon
Anatomical Term:	whole organism
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA