FIGURE

Fig. 3

ID

ZDB-FIG-081013-46

Publication

Lele et al., 1999 - Disruption of zebrafish somite development by pharmacologic inhibition of hsp90

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Fig. 3

Expression of hsp90α during early somite development as detected by in situ hybridization analysis. (A) 3- to 4-somite stage, dorsal view. (B) 16 somite stage, dorsal view. (C) Cross section through unsegmented paraxial mesoderm prior to somite formation. (D) Longitudinal section through the dorsal–ventral midline at the location of the most recently formed somite. Strong constitutive expression of hsp90α is confined to the adaxial cells (closed arrows). Very low levels of hsp90α mRNA are sometimes detectable in the lateral presomitic cells which lie distal to the adaxial cells (C). Open arrows in D indicate the most recently formed somite furrow. n, notochord. Scale bar in A and B, 100 μm. Scale bar in C and D, 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 210(1), Lele, Z., Hartson, S.D., Martin, C.C., Whitesell, L., Matts, R.L., and Krone, P.H., Disruption of zebrafish somite development by pharmacologic inhibition of hsp90, 56-70, Copyright (1999) with permission from Elsevier. Full text @ Dev. Biol.