FIGURE

Fig. 6

ID

ZDB-FIG-071102-11

Publication

Hadzhiev et al., 2007 - Hedgehog signaling patterns the outgrowth of unpaired skeletal appendages in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6

A functional midline with expression of shh is required for the ACFP. A, B, GFP expression domains including that in the floor plate indicating shh expression (arrowhead) and the ACFP marker (arrow) are present in wild type (A) and lost in flh^/-embryos (B). C, D, The fin fold mesenchyme as indicated by msx-c expression is unaffected in flh^-/-embryos. The ragged appearance of the fin fold is due to shrinkage during the whole mount in situ hybridization procedure. E, F, presence of residual floor plate cells (arrowheads) are coupled with rescue of the ACFP (arrows). Red arrowheads in F indicate the position of floor plate cells as detected in the fluorescent image. All images of caudal fin regions anterior to the left. Bright field views are shown on the left panels and fluorescence images using GFP filter on the right (A, B, E, F).

Expression Data

Genes:	GFP msx3
Fish:	sb15Tg noto^n1/n1; sb15Tg
Anatomical Terms:	caudal fin floor plate mesenchyme median fin fold
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	noto^n1/n1; sb15Tg
Observed In:	caudal fin mesenchyme median fin fold
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.