ZFIN ID: ZDB-FIG-070925-52
Albertson et al., 2007 - Fgf8 haploinsufficiency results in distinct craniofacial defects in adult zebrafish. Developmental Biology   306(2):505-515 Full text @ Dev. Biol.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage: Adult

Fig. 2 Fig. 2. Mandibular symmetry and cranial suture patterning is altered in aceti282a/+ zebrafish. The cranial midline was defined as the midline of the neurocranium. In homozygous wild-type zebrafish, the mandibular symphysis (m) was oriented along the cranial midline (A). In aceti282a/+ animals, however, the mandible exhibited pronounced asymmetry (B). The interfrontal (if) and sagittal (s) sutures in aceti282a/+ zebrafish also deviated significantly from the midline compared to wild-type siblings (F-ratio = 20.8, p < 0.0001, and F-ratio = 8.36, p = 0.006, respectively).

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
fgf8ati282a/+ standard conditions Adult chondrocranium bilateral symmetry, abnormal
Adult ventral mandibular arch bilateral symmetry, abnormal
Adult ventral mandibular arch malformed, abnormal
Acknowledgments:
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Reprinted from Developmental Biology, 306(2), Albertson, R.C., and Yelick, P.C., Fgf8 haploinsufficiency results in distinct craniofacial defects in adult zebrafish, 505-515, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.