FIGURE

Fig. 6

ID

ZDB-FIG-070920-46

Publication

Sharma et al., 2005 - Role of Fyn kinase in signaling associated with epiboly during zebrafish development

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Fig. 6

Effect of Fyn^K299M on the ability of blastomeres to participate in epiboly. Embryos were collected at the 16-cell stage and single blastomeres were injected with a mixture of calcium green-dextran and mRNA (4.5 pg). The embryos were cultured at 28°C and examined by confocal fluorescence microscopy at 5, 7, and 9 hpf. The embryo shown in the upper panels was injected with c-Fyn mRNA and the fluorescent cells migrated toward the vegetal pole with the advancing blastoderm. The embryos shown in the middle and lower panels were injected with Fyn^K299M mRNA and in these cases, the fluorescent cells remained near the animal pole.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 285(2), Sharma, D., Holets, L., Zhang, X., and Kinsey, W.H., Role of Fyn kinase in signaling associated with epiboly during zebrafish development, 462-476, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.