FIGURE

Fig. 9

ID

ZDB-FIG-070502-35

Publication

Hagos et al., 2007 - Time-dependent patterning of the mesoderm and endoderm by Nodal signals in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 9

Cell fate specification is accelerated when Nodal levels are increased. Embryos were injected with sqt mRNA at the 1–4 cell stage and treated with DMSO (A1-C1) or SB-431542 at various time points (A2-C7). Sqt induces ubiquitous expression of gsc and sox17 (B1, C1) but not flh (A1). (A2-C2) SB-431542 treatment at MBT blocks expression of each of these markers. flh is strongly expressed in embryos treated at 3.7 h (A3), but fades at later time points (A4-7). gsc expression is first detected in embryos treated at 3.7 h (B3), and expands at later time points (B4-7). sox17 expressing cells are first detected when embryos are treated at 4.3 h (C4), and expands at later time points (C5-7). Animal pole views at 10 h.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.